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目的观察白藜芦醇对人宫颈癌Hela细胞凋亡的影响。方法采用TUNEL法检测不同浓度的白藜芦醇诱导体外培养的Hela细胞凋亡情况。结果浓度大于50μmol/L的白藜芦醇处理Hela细胞后,细胞凋亡特征明显可见,并呈时间和剂量依赖关系。结论白藜芦醇对人宫颈癌Hela细胞有明显的促凋亡作用。
Objective To observe the effect of resveratrol on the apoptosis of human cervical carcinoma Hela cells. Methods TUNEL method was used to detect the apoptosis of Hela cells induced by different concentrations of resveratrol in vitro. Results After treated with resveratrol at a concentration of more than 50 μmol / L, the apoptotic characteristics of Hela cells were clearly observed in a time-and dose-dependent manner. Conclusion Resveratrol has obvious apoptosis-promoting effect on human cervical cancer Hela cells.