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目的:观察生脉注射液联合弥可保治疗糖尿病周围神经病变的临床疗效,探讨其治疗机理。方法:64例患者随机分为2组,对照组予弥可保(500 pg/片),3次/d,1片/次,治疗组在对照组基础上加用生理盐水250 mL+生脉注射液30 mL静滴,1次/d,30天后观察2组血液流变学、神经传导速度等指标。结果:治疗组总有效率87.49%,对照组总有效率59.37%,2组比较有显著性差异(P<0.01)。结论:生脉注射液联合弥可保能明显改善糖尿病周围神经病变血液流变学、神经传导速度等指标,比单用弥可保效果更好。
Objective: To observe the clinical curative effect of Shengmai injection combined with Miqibao on diabetic peripheral neuropathy and to explore its therapeutic mechanism. Methods: Sixty-four patients were randomly divided into two groups. The control group was treated with 500 μg / tablet, 3 times / d, and 1 tablet / time. The treatment group was given saline 250 mL plus Shengmai Injection Liquid 30 mL intravenous infusion, once / d, 30 days after the observation of two groups of blood rheology, nerve conduction velocity and other indicators. Results: The total effective rate was 87.49% in the treatment group and 59.37% in the control group. There was significant difference between the two groups (P <0.01). Conclusion: Shengmai injection combined with miconazole can significantly improve the diabetic peripheral neuropathy such as hemorheology, nerve conduction velocity and other indicators, the effect is better than the single use of Mocobo.