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近日,来自荷兰癌症研究所的科研人员在国际学术期刊Cell Reports上发表了一项最新研究进展,他们在小细胞肺癌小鼠模型上找到了一种促进肿瘤发生和发展的重要转录因子,并且也在人类肿瘤样本中对该分子的表达情况与肿瘤进展之间的相关性进行了验证。该研究或为小细胞肺癌治疗和疾病进展诊断提供新的靶点和诊断标记。小细胞肺癌(SCLC)是一种恶性的神经内分泌肿瘤,目前还没有文献报道找到有效的治疗方法。该研究团队在之前研究中通过抑制Rb1和
Recently, researchers from the Netherlands Cancer Institute published a new research report in the international academic journal Cell Reports. They found an important transcription factor in the mouse model of small cell lung cancer to promote tumorigenesis and development, and The correlation between the expression of this molecule and the progression of tumors was validated in human tumor samples. This study provides new targets and diagnostic markers for the treatment of small cell lung cancer and the diagnosis of disease progression. Small cell lung cancer (SCLC) is a malignant neuroendocrine tumor. Up to now, no effective treatment has been reported in the literature. The research team in previous studies by inhibiting Rb1 and