论文部分内容阅读
目的探讨采用抗生素降阶梯治疗对慢性阻塞性肺疾病合并重症肺炎的疗效。方法 94例慢性阻塞性肺疾病合并重症感染患者随机分为实验组和对照组。实验组采用降阶梯治疗,对照组采用常规抗生素治疗,比较两组疗效。结果降阶梯的治疗组改善临床症状、体征、住院天数、中性粒细胞百分比、CRP均低于常规抗生素治疗的对照组,差异有统计学意义(P<0.05),动脉氧分压、氧饱和度显著上升,差异有统计学意义(P<0.05)。结论抗生素降阶梯治疗减少不适当抗生素治疗的比例,缩短治疗时间,改善临床症状,提高慢性阻塞性肺疾病合并重症肺炎的救治效果,同时避免抗生素滥用和医疗资源浪费。
Objective To investigate the effect of antibiotic descending step on chronic obstructive pulmonary disease complicated with severe pneumonia. Methods 94 patients with chronic obstructive pulmonary disease complicated with severe infection were randomly divided into experimental group and control group. The experimental group was treated with descending ladder, while the control group was treated with conventional antibiotics. The curative effect was compared between the two groups. Results The clinical symptoms, signs, days of hospitalization, percentage of neutrophils, CRP in the descending ladder group were significantly lower than those in the control group (P <0.05). The arterial partial pressure of oxygen, oxygen saturation Degrees significantly increased, the difference was statistically significant (P <0.05). Conclusions The antibiotic descending ladder can reduce the proportion of inappropriate antibiotics, shorten the treatment time, improve the clinical symptoms, improve the therapeutic effect of COPD with severe pneumonia, and avoid the abuse of antibiotics and the waste of medical resources.