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目的观察应用奥曲肽治疗各种原因引起的急性上消化道出血的疗效。方法对46例上消化道大出血患者采用奥曲肽注射液0.1 mg配0.9%氯化钠注射液20 ml缓慢静脉推注,再以0.025mg/h静脉滴注24~72 h。结果 24 h及72 h止血率分别为56%和40%,治疗3 d总有效率为96%。未发现明显副反应。结论奥曲肽治疗上消化道出血疗效好,安全可靠,值得在基层医院临床急救中推广使用。
Objective To observe the curative effect of octreotide on acute upper gastrointestinal bleeding caused by various causes. Methods 46 cases of upper gastrointestinal bleeding in patients with octreotide injection 0.1 mg 0.9% sodium chloride injection 20 ml slow intravenous injection, and then intravenous infusion of 0.025 mg / h 24 ~ 72 h. Results The hemostasis rates at 24 h and 72 h were 56% and 40%, respectively. The total effective rate was 96% after 3 days of treatment. No obvious side effects were found. Conclusions Otreotide in the treatment of upper gastrointestinal bleeding is effective, safe and reliable, which is worth popularizing in the first aid of primary hospital.