Genetic alterations in head and neck squamous cell carcinoma:The next-gen sequencing era

• 作 者: Thien Khanh Nguyen N Gopalakri
• 机 构: Duke-NUSGraduateMedicalSchool,DepartmentofSurgicalOncology
• 出 处: 世界医学遗传学杂志
• 发表日期: 2013年4期
• 关键词: Head and neck SQUAMOUS cell carcinoma TP53 Ras/PIK3CA NOTCH1/p63 HPV/E6/E7/Rb/CD

Head and neck squamous cell carcinoma is the sixth most common cancer in the world with approximately 650000 new cases diagnosed annually.Next-generation molecular techniques and results from phase 2 of the Cancer Genome Atlas becoming available have dras