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该文采用pH滴定法,以pH5.0为起始pH,pH8.2为终点指示pH,用NaOH直接滴定,测定了羟乙膦酸钠的含量.该方法简便、准确快速,平均回收率为100.72％,RSD为0.23％(n＝6).“,”Etidronate disodium was determined quantitatively by pH titraion method. The initial pH was pH 5.0 and the terminal pH was pH 8.2, with 0. 1mol/L of NaOH as the titration sotution. This method was simple, accurae and quick. The average recovery and the retative standard diviation were 100.72%and 0.23%(n=6)