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格林－巴利综合征（GBS）病因及发病机理探讨。方法采用ELISA法测定30例格林－巴利综合征（GBS）患者血清抗空肠弯曲菌抗体（Cj－Ab）及GM1抗体（GM1－Ab），并与临床严重程度进行相关分析。结果GBS组血清Cj－IgG、IgM阳性率分别为60％、30％，较对照组30．8％和7．7％为高，两组差异有显著性，P值均小于0．05。GBS组GM1－IgG阳性率为38％，而对照组为2．1％，经检验两者差异也有显著性，P值均小于0．05。结论Cj近期感染与GBS发病相关，而GBS的两种抗体与临床严重程度无明显关系。
Etiology and pathogenesis of Guillain - Barre Syndrome. Methods Serum anti-C j-Ab antibody and GM1 antibody (GM1-Ab) were determined in 30 patients with Guillain-Barre Syndrome (GBS) by ELISA. The correlation was analyzed with the clinical severity. Results The positive rates of serum Cj-IgG and IgM in GBS group were 60% and 30%, respectively, which were higher than those in control group (30.8% and 7.7%). There was significant difference between the two groups with P values less than 0.05. The positive rate of GM1-IgG in GBS group was 38%, while that of the control group was 2.1%. The difference between the two groups was also significant (P <0.05). Conclusion The recent infection of Cj is related to the pathogenesis of GBS, while the two antibodies of GBS have no significant relationship with the clinical severity.