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1803例肺结核病患者(初治588例,复治1215例)对七种抗结核药物的耐药产生率与每种药物使用时间的关系进行分析。在1803例中未服用药物项内之耐药率以链霉素最高为11.5%:乙胺丁醇最低为0.4%;其他药物依次为异烟肼5.4%;对氨柳酸钠5.2%;丙硫异菸胺3.5%;卡那霉毒2.8%;利福平1.0%。对服用过的药物的耐药率则随着服药时间延长而有不同程度上升,成正比关系,其中以利福平最快;乙胺丁醇最慢,其余为链霉素、异烟肼,卡那霉素,对氨柳酸钠、丙硫异菸胺。
1803 patients with tuberculosis (initial treatment of 588 cases, retreatment of 1215 cases) of the seven anti-TB drug resistance rates and the relationship between each drug use time were analyzed. In 1803 cases, the drug resistance rate in non-medication items was highest with streptomycin 11.5%: the lowest was ethambutol 0.4%; the other medicines were isoniazid 5.4%; sodium salicylate 5.2%; C Thiisonamide 3.5%; kanamycin 2.8%; rifampicin 1.0%. The rate of resistance to medication taken with the medication time is extended to varying degrees, a direct relationship, of which rifampicin fastest; ethambutol the slowest, the rest for streptomycin, isoniazid, Kanamycin, sodium salicylate, prothionamide.