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在山西省1960年使用Ⅰ、Ⅱ型脊髓灰白質炎减毒活疫苗时期,选择太原市一部分1至6岁儿童采血作抗体水平调查,一般抗体阳性率低,有69.2％以上的幼儿无脊髓灰白質炎抗体的存在,敏感儿的比值高。服用疫苗后一个月无论Ⅰ型或Ⅱ型病毒抗体全部转为阳性,而且除个别例外几乎全部持续阳性至一年以上。服苗前原有部分抗体的儿童抗体水平也有显著增高。总的抗体增长率(4倍以上)Ⅰ型服后一个月时为96.5％,六个月时87.5,一年时85.0％;Ⅱ型服后一个月96.5％;六个月93.7％,一年为90.0％。一年中抗体滴度是平稳和缓和的下降,表现出良好的持续性,由此认为山西省1960年使用脊髓灰白質炎减毒活疫苗的免疫效果是良好的,值得大力推广使用。
In 1960, when using attenuated live type Ⅰ and Ⅱ poliovirus vaccine in Shanxi Province, some children from 1 to 6 years old in Taiyuan City were selected for antibody level survey. The prevalence of common antibody was low, 69.2% of whom had no spinal gray The presence of anti-inflammatory antibodies, high sensitivity of children. One month after taking the vaccine, either type I or type II virus antibodies turned positive, with almost all of them continuing to be positive for more than one year except for a few exceptions. Pre-service part of the original antibody antibody levels of children have also been significantly higher. The total antibody growth rate (more than 4 times) was 96.5% at the first month of type I service, 87.5 at six months and 85.0% at one year; 96.5% at one month after type II service; 93.7% at six months 90.0%. Antibody titer in a year is a steady and gentle decline, showing a good continuity, thus that the immune effect of live attenuated virulent myeloablative vaccine in Shanxi Province in 1960 is good, it is worth to vigorously promote the use of.