论文部分内容阅读
目的 :研究柔性纳米脂质体对环孢素经皮渗透的促进作用。方法 :采用改进的Ｆｒａｎｚ扩散池体外经皮渗透实验技术 ,比较普通纳米脂质体、含有表面活性剂胆酸钠的柔性纳米脂质体以及胆酸钠胶团溶液对环孢素的经皮渗透促进作用。结果 :将脂质体胶体溶液非封闭性应用于离体小鼠皮
Objective: To study the promoting effect of flexible nanoliposomes on cyclosporine transdermal penetration. Methods: The modified Franz diffusion cell in vitro transdermal permeation test was used to compare the effects of common nano-liposomes, flexible nano-liposomes containing sodium cholate and the sodium cholic acid micelles solution on the transdermal penetration of cyclosporine enhancement. Results: The liposome colloidal solution was applied to the isolated mouse skin in a non-occlusive manner