首发症状为视力下降的儿童成人型慢性髓细胞性白血病1例

• 作 者: Rudolph G Haritoglou C Schmid I. 张少娟
• 机 构: Ludwig-Maximilians-University Munich Department of Ophthalmology,Mathildenstr 8 Munich 80336 German
• 出 处: 世界核心医学期刊文摘.眼科学分册
• 发表日期: 2006年02期
• 关键词: 成人型 白血病浸润 羟基脲 费城染色体 眼底镜检查 视网膜病变 眼科检查 干预性 眼科医生 干细胞移植

PURPOSE: To report the unusual case of retinal leukemic infiltration in a child with adult-type chronic myelocytic leukemia. DESIGN: Interventional case report. METHODS: Complete ophthalmologic examination, including visual acuity measurement and funduscopy. The diagnosis was established by blood cell counts and confirmed by a positive Philadelphiachromosome translocation (t [9,22]). Treatment consisted of hydroxyurea and stem-cell transplantation. RESULTS: After therapy, complete regression of the retinal lesion was observed with full recovery of visual acuity. CONCLUSION: This case underlines the importance of interdisciplinary cooperation between ophthalmologists and pediatric oncologists in the diagnosis and treatment of this disease.

PURPOSE: To report the unusual case of retinal leukemic infiltration in a child with adult-type chronic myelocytic leukemia. METHODS: Interventional case report. METHODS: Complete ophthalmologic examination, including visual acuity measurement and funduscopy. The diagnosis was established by blood cell counts and confirmed by a positive Philadelphia chromosome transfer (t [9,22]). Treatment: After therapy, complete regression of the retinal lesion was observed with full recovery of visual acuity. CONCLUSION: This case underlines the importance of interdisciplinary cooperation between ophthalmologists and pediatric oncologists in the diagnosis and treatment of this disease.