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四物汤出自《太平惠民和剂局方》,由当归、川芎、白芍、熟地组成,为补血方剂的代表方,广泛用于治疗冲任虚损,月经不调,崩中漏下及血瘕块硬,时发疼痛等;一方随证加减,可统治诸种血证;方中川芎、当归为著名药对.既往对四物汤的药理及药效学研究较多,但尚无人研究四物汤的药物动力学.1991年黄氏等提出了“证治药动学”新假说,其中的“复方药动学”首次提出方剂配伍时可彼此影响体内的化学成分的浓度及疗效;他们还先后进行了川芎煎剂及川芎
Siwutang comes from the “Taiping Huimin Hezhi Bureau Party”. It is composed of Angelica sinensis, Rhizoma Chuanxiong, Angelica dahurica, and Rehmannia. It is a representative of the blood-enriching prescription and is widely used to treat Chongren Deficiency, irregular menstruation, and missing in the collapse. Blood lumps are hard and often painful; one party can administer various blood syndromes with addition and subtraction of the card; Fang Zhongchuan wolfberry and angelica are famous medicine pairs. Previous studies on the pharmacology and pharmacodynamics of Siwu Tang were numerous, but there were no People studied the pharmacokinetics of Siwu Tang. In 1991, Huang et al proposed the new hypothesis of “Pharmaceuticals for Syndrome Pharmacokinetics”, in which “Compound pharmacokinetics” first proposed the compatibility of formulas to influence the concentration of chemical components in the body. Efficacy; they also successively performed Chuanxiong decoction and Chuanxiong