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本文对３３例支气管哮喘发作期患儿进行了免疫球蛋白Ｅ、Ｇ、Ａ、Ｍ以及ＩｇＧ亚类的测定，设健康儿童对照组进行比较，结果表明：哮喘组ＩｇＥ平均值为７４７．３１ＩＵ／ｍｌ，对照组平均值为１０１．３４ＩＵ／ｍｌ，即哮喘患儿ＩｇＥ值明显高于对照组（Ｐ＜０．００１）。哮喘组ＩｇＧ亚类Ｇ１、Ｇ４分别为３．５３±１．４９、０．３３±０．１２，而对照组分别为４．９２±０．８３、０．２８±０．０８，两组之间有显著性差异（Ｐ＜０．００１）、（Ｐ＜０．０５）。Ｇ２、Ｇ３与对照组之间差异不显著。哮喘组ＩｇＧ值明显低于正常组，ＩｇＡ、ＩｇＭ值属正常范围。结果提示，小儿支气管哮喘发作期的体液免疫功能是紊乱的。
In this paper, 33 cases of children with bronchial asthma attack were immunoglobulin E, G, A, M and IgG subclasses of the determination of healthy children were compared with the control group, the results showed that: the average IgE in asthma group was 747.31IU / ml, the average value of the control group was 101.34IU / ml, that is, the IgE in children with asthma was significantly higher than that in the control group (P <0.001). The IgG subclasses G1 and G4 in asthma group were 3.53 ± 1.49 and 0.33 ± 0.12, while those in the control group were 4.92 ± 0.83 and 0.28 ± 0.08, respectively There was significant difference (P <0.001), (P <0.05). There was no significant difference between G2 and G3 and control group. IgG in asthma group was significantly lower than the normal group, IgA, IgM values are within the normal range. The results suggest that childhood humoral immune function during bronchial asthma exacerbation.