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目的探讨缺血性脑卒中(CIS)患者分型及颅内血管狭窄的危险因素,为预防脑卒中的再发提供参考依据。方法于2006年3月—2007年2月在哈尔滨医科大学附属第二医院神经内科对首次住院治疗的135例CIS患者进行经颅多普勒超声(TCD)检测,并进行牛津郡社区脑卒中项目(OCSP)分型,运用logistic回归模型分析颅内血管狭窄的危险因素。结果 135例CIS患者OCSP分型比例由大至小依次为后循环梗塞(31.85%)、腔隙性梗塞(31.11%)、部分前循环梗塞(25.93%)、完全前循环梗塞(11.11%);CIS患者颅内血管狭窄率为23.70%(32/135);多因素logistic回归分析结果表明,高血压病史、糖尿病病史、OCSP分型为完全前循环梗塞是CIS患者颅内血管狭窄的危险因素。结论 CIS患者应预防高血压、糖尿病等疾病的发生和发展,并及时给予OCSP分型,以便有针对性地防止颅内血管狭窄的发生及脑卒中的再发。
Objective To investigate the risk factors of type and intracranial vascular stenosis in patients with ischemic stroke (CIS) and provide a reference for preventing the recurrence of stroke. Methods From January 2006 to February 2007, 135 cases of first-time hospitalized CIS patients underwent transcranial Doppler ultrasonography (TCD) in Department of Neurology, the Second Affiliated Hospital of Harbin Medical University and the Oxfordshire Community Stroke Project (OCSP) classification, the use of logistic regression model analysis of risk factors for intracranial vascular stenosis. Results The percentages of OCSP in 135 cases of CIS were as follows: posterior circulation infarction (31.85%), lacunar infarction (31.11%), partial anterior circulation infarction (25.93%) and complete anterior circulation infarction (11.11%). CIS patients with intracranial vascular stenosis rate was 23.70% (32/135); multivariate logistic regression analysis showed that history of hypertension, history of diabetes, OCSP classification of complete anterior circulation infarction is a CIS risk factors for intracranial vascular stenosis. Conclusion CIS patients should prevent the occurrence and development of diseases such as hypertension and diabetes mellitus, and timely give OCSP classification in order to prevent the occurrence of intracranial vascular stenosis and the recurrence of stroke.