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目的:探讨NICU病房中毛细血管渗漏综合征(CLS)发生的危险因素。方法:回顾性分析NICU中发生CLS患儿45例(病例组)的临床资料,另外选取同时入住NICU未发生CLS患儿50例作为对照组。对CLS发生的因素先进行单因素分析,有统计学意义的因素进行Logistic回归分析,确定CLS发生的独立因素。结果:单因素分析显示,两组之间败血症发生率、乳酸值增高的发生率,机械通气超过7天,PEEP>6 cmH2O,PIP>22 cmH2O发生率有统计学差异,而Logistic回归分析显示,败血症和通气时间超过7天是CLS的独立危险因素。结论:败血症、机械通气持续时间是CLS发生的独立危险因素。
Objective: To explore the risk factors of capillary leak syndrome (NICU) in NICU ward. Methods: The clinical data of 45 cases (cases group) with CLS in NICU were retrospectively analyzed. Another 50 cases without CLS in NICU were selected as the control group. The factors of CLS were univariate analysis, statistically significant factors Logistic regression analysis to determine the occurrence of CLS independent factors. Results: Univariate analysis showed that the incidence of sepsis and lactate increased between the two groups. The incidence of mechanical ventilation over 7 days, PEEP> 6 cmH2O and PIP> 22 cmH2O were statistically different. Logistic regression analysis showed that the incidence of sepsis, Sepsis and aeration for more than 7 days are independent risk factors for CLS. Conclusions: Sepsis and duration of mechanical ventilation are independent risk factors for CLS.