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目的观察高血压患者血清尿酸水平的改变及其临床意义。方法检测166例高血压患者及148例正常血压者的血清尿酸水平。结果高血压病患者血清尿酸水平明显高于正常血压者(P<0.01),2级高血压患者血尿酸水平明显高于1级高血压患者(P<0.01),3级高血压患者血尿酸水平又明显高于2级高血压患者(P<0.01)。结论高血压患者血清尿酸水平升高,血清尿酸水平升高的程度与高血压的临床分级有关,动态监测血清尿酸水平有助于了解高血压病的病情发展,治疗高血压的同时要高度重视高尿酸血症的治疗。
Objective To observe the change of serum uric acid level in patients with hypertension and its clinical significance. Methods Serum uric acid levels were measured in 166 hypertensive patients and 148 normal subjects. Results The level of serum uric acid in patients with essential hypertension was significantly higher than that of patients with normal blood pressure (P <0.01). The level of serum uric acid in patients with grade 2 hypertension was significantly higher than that of patients with grade 1 hypertension (P <0.01) Which was significantly higher than that of grade 2 hypertension patients (P <0.01). Conclusions The serum uric acid level is elevated in patients with essential hypertension and the level of serum uric acid is related to the clinical grade of hypertension. The dynamic monitoring of serum uric acid level can help to understand the progression of hypertension, and treat hypertension with high attention Treatment of uric acid.