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[目的 ]对福建省钩端螺旋体病流行特征进行分析 ,为我省钩端螺旋体病防治提供科学依据。 [方法 ]对历年来流行趋势、流调资料、监测结果进行比较分析。 [结果 ]发病率 5 0～ 70年代初呈上升趋势 ,个别年份发病率高达16 .43/ 10万 ,70年代中期至 90年代末明显下降 ;发病地区有从沿海丘陵地区移向内地山区的趋势 ;流行季节从双峰型转为单峰型。 5 0～ 70年代流行菌群以以波摩那群、爪哇群、秋季热群为主 ,90年代则以七日热群、巴达维亚群、秋季热群和澳洲群为主 ,血清抗体检测各型均有检出 ,以秋、黄、巴、七为主。 [结论 ]近年福建省钩体病发病特征及菌群分布发生变化 ,疫苗配方应改为七日热群和巴达维亚群为主。
[Objective] To analyze the epidemic characteristics of leptospirosis in Fujian Province and provide a scientific basis for prevention and treatment of leptospirosis in our province. [Method] A comparative analysis was made on the prevailing trend, flow control data and monitoring results over the years. [Results] The incidence increased from the early 1970s to the early 1970s, with the incidence of 16.43 / 100 000 in some years, which was significantly decreased from the mid-1970s to the late 1990s. The incidence in the affected areas shifted from the hilly coastal areas to the inland mountainous areas ; The popular season changed from bimodal to unimodal. Populations in the 1950s and 1970s were dominated by the Pomona, Java and autumn fall heat groups. In the 1990s they were dominated by the seven day fever group, the Batavia subgroup, the autumn heat subgroup and the Australian subgroup. The serum antibody test All types are detected, with autumn, yellow, Pakistan, seven-based. [Conclusion] The incidence and distribution of leptospirosis in Fujian Province have changed in recent years. The vaccine formulation should be changed into the seven-day fever group and Batavia group.