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四氯乙烯（ＰＣＥ）属氯代烯烃化合物，广泛用作干洗剂和工业去污剂等。因此，ＰＣＥ接触人群日益增多。ＰＣＥ可引起肝脏和肾脏等多器官系统损伤〔１〕。已知，ＰＣＥ的毒性主要与其在肝脏中生物转化产物三氯乙酸（ＴＣＡ）有关〔２〕。ＴＣＡ通过肾脏由尿排出，可能会引起肾
Perchlorethylene (PCE) is a chloroolefin compound, widely used as a dry cleaning agent and industrial detergent. Therefore, PCE exposure to the growing population. PCE can cause multiple organ systems such as the liver and kidneys [1]. It is known that the toxicity of PCE is mainly related to its biotransformation product trichloroacetic acid (TCA) in the liver [2]. TCA is excreted by the kidneys from the urine and may cause kidney damage