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本文用RIA对肾性尿毒症和正常人各16例作了血浆ANP测定。发现肾性尿毒症血浆ANP明显高于对照组;ANP与病程呈正相关;不同病因及有无高血压ANP差别不显著。本文结果表明尿毒症血浆ANP升高是心脏对钠水潴留的一种代偿反应,也是体内钠水潴留及血容量增加的标志。
In this paper, RIA of renal uremic and normal in 16 cases of plasma ANP determination. Found that renal plasma uremic ANP was significantly higher than the control group; ANP and duration of the disease was positively correlated; different causes and with or without hypertension ANP difference was not significant. The results of this paper show that elevated plasma ANP of uremia is a compensatory response to sodium and water retention in the heart and is also a hallmark of sodium retention and increased blood volume in the body.