论文部分内容阅读
目的:探讨川崎病患儿合并冠状动脉病变的危险因素。方法:回顾性分析2002～2008年收治的川崎病患儿131例,将其分成冠状动脉病变组和非冠状动脉扩张组,分别从性别、年龄、临床表现、实验室检查、治疗等方面入手分析冠状动脉病变发生的危险因素。结果:发生冠状动脉病变与未发生冠状动脉病变的患儿在性别、年龄等方面比较差异无统计学意义,两组患儿在C反应蛋白、血沉、血红蛋白水平及免疫活性测定上比较差异有统计学意义。结论:单因素分析表明C反应蛋白明显增高,高血沉是发生冠状动脉病变的危险因素。病程早期未予丙种球蛋白治疗的患儿并发冠状动脉病变危险性明显增高。
Objective: To explore the risk factors of coronary artery disease in children with Kawasaki disease. Methods: A retrospective analysis of 131 children with Kawasaki disease admitted from 2002 to 2008 was divided into coronary artery disease group and non-coronary artery dilatation group, respectively, from the aspects of gender, age, clinical manifestation, laboratory examination and treatment Coronary artery disease risk factors. Results: There was no significant difference in sex, age, etc. between children with coronary artery disease and without coronary artery disease. There were statistically significant differences between the two groups in the determination of C-reactive protein, ESR, hemoglobin and immunocompetence Significance of learning. Conclusion: Univariate analysis showed that C-reactive protein was significantly elevated, and ESR was a risk factor for coronary artery disease. The course of the disease was not early gamma globulin in children with coronary artery disease risk was significantly higher.