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[目的]了解我县开展“三网监测”工作以来,出生缺陷发生情况及影响因素。[方法]按照《中国出生缺陷医院监测方案》要求,对县级2002~2009年2家医院出生的孕28周至出生后7 d的围产儿进行监测。[结果]2002~2009年监测围产儿7 236人,发生出生缺陷的85例,出生缺陷发生率11.75‰。出生缺陷发生率2004年最低,2007年最高(P<0.01);出生缺陷发生率男性10.58‰,女性13.02‰(P>0.05)。主要缺陷为肢体短缩(占17.65%)、唇腭裂(占16.47%)、马蹄足内翻(占8.24%)、脑膨出(占7.06%)、无脑儿(占5.88%)。[结论]加强婚前检查,孕期保健、产前检查、产前诊断,可降低出生缺陷的发生。
[Objective] To understand the occurrence and influencing factors of birth defects in our county since the work of “three networks monitoring ”. [Methods] According to the requirements of “China Birth Defective Hospital Surveillance Program”, the perinatal infants born at two hospitals in the county from 2002 to 2009 and pregnant from 28 weeks to 7 days after birth were monitored. [Results] From 2002 to 2009, 7 236 perinatal babies were monitored. There were 85 birth defects and the incidence of birth defects was 11.75 ‰. The incidence of birth defects was the lowest in 2004 and the highest in 2007 (P <0.01). The incidence of birth defects was 10.58% in males and 13.02% in females (P> 0.05). The main defects were limb shortening (17.65%), cleft lip and palate (16.47%), clubfoot varus (8.24%), encephalocele (7.06%) and no brain (5.88%). [Conclusion] Strengthening premarital examination, prenatal care, prenatal examination and prenatal diagnosis can reduce the incidence of birth defects.