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目的探讨术前新辅助区域化疗联合放疗治疗进展期低位直肠癌的疗效。方法 2004年3月—2007年6月共对26例进展期低位直肠癌行术前新辅助区域化疗联合放疗。结果术后发生吻合口漏2例(7.69%),吻合口狭窄1例(3.85%),无手术死亡。结论术前区域化疗联合放疗是治疗低位直肠癌的一种有效治疗手段,可以提高手术切除率和保肛率。
Objective To investigate the effect of preoperative neoadjuvant regional chemotherapy combined with radiotherapy in the treatment of advanced low rectal cancer. Methods From March 2004 to June 2007, 26 patients with advanced low rectal cancer underwent preoperative neoadjuvant chemotherapy combined with radiotherapy. Results Anastomotic leakage occurred in 2 cases (7.69%) and anastomotic stenosis in 1 case (3.85%). There was no operative death. Conclusion Preoperative regional chemotherapy combined with radiotherapy is an effective treatment for low rectal cancer, which can improve the rate of resection and anal sphincter preservation.