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目的:研究全肠外营养(TPN)支持及给予单瓶串联输注营养成分对食管癌根治术后患者疗效的影响,探讨合理的肠外营养支持方案。方法:收集食管癌根治术后患者96例临床资料,术后48h内给予TPN支持作为研究组(43例),术后48h内给予单瓶串联输注营养成分作为对照组(53例)。SPSS15.0软件包汇总分析2组患者术后给予的营养成分、治愈率等资料。结果:2组患者的手术部位、手术医师的专业水平、术后住院天数、术后ICU观察时间、术后进食时间、术后并发症发生率差异均无统计学意义(P>0.05)。2组患者所用的脂肪乳、氨基酸、葡萄糖、总能量及营养成分输注量差异均有统计学意义(P<0.01)。研究组出院治愈率为100%,对照组为83.02%,研究组的治愈率高于对照组(P<0.05)。结论:食管癌根治术后患者应用TPN支持较之给予单瓶串联输注营养成分,治愈率明显提高。
Objective: To study the effect of total parenteral nutrition (TPN) support and single bottle infusion on the curative effect of esophageal cancer patients after radical operation and explore the reasonable parenteral nutrition support plan. Methods: Ninety - six patients with esophageal cancer after radical resection were enrolled in this study. TPN support was given within 48 hours after operation in the study group (n = 43). One - bottle serial infusion of nutrients was given as control group (n = 53) within 48 hours after operation. SPSS15.0 software package summarizes the two groups of patients after giving the nutritional content, cure rate and other information. Results: There was no significant difference in the surgical site, surgeon’s professional level, postoperative hospital stay, postoperative ICU observation time, postoperative eating time and the incidence of postoperative complications between the two groups (P> 0.05). There was significant difference between the two groups in the amount of fat emulsion, amino acids, glucose, total energy and nutrient infusion (P <0.01). The study group discharged 100% cure rate, the control group was 83.02%, the cure rate of the study group was higher than the control group (P <0.05). Conclusions: The cure rate of patients with esophageal cancer after applying TPN support is better than that of single-bottle serial infusion of nutrients.