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观察通络糖泰,对糖尿病性周围神经病变(DPN)64例(TG)甲皱微循环及足背静脉血气分析的影响,并与达美康加肌醇治疗的65例(RG)对照。结果表明TG对甲皱微循环血管轮廓不清、袢周出血的疗效优于RG(P<0.05),袢顶瘀血TG极显著优于RG(P<0.001),对降低足背静脉氧分压与氧饱和度TG优于RG(P<0.001),升高二氧化碳分压二者均有效(TGP<0.001,RGP<0.05)。提示改善微循环及组织缺血缺氧是通络糖泰有效治疗DPN的机理之一。
Observe the effect of Tongluotangtai on the analysis of 64 patients with diabetic peripheral neuropathy (DPN), nailfold microcirculation, and dorsal venous blood gas analysis, and compare it with 65 patients with dexamethasone and inositol. The results showed that the efficacy of TG was better than that of RG (P<0.05) in the unclear arterial wrinkles and the periarthritis hemorrhage (P<0.05). The TG of the dome was superior to that of RG (P<0.001). The PT of oxygen in the dorsal venous blood and oxygen saturation was better than that of RG (P<0.001), and the increase of carbon dioxide partial pressure was both effective (TGP<0.001, RGP<0.05). It is suggested that the improvement of microcirculation and tissue ischemia and hypoxia is one of the mechanisms by which Tongluo Tang can effectively treat DPN.