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为了探讨青壮年猝死综合征（SMDS）的死亡原因与心性猝死之间的关系，作者对SMDS、冠心病、非心血管疾病死亡（正常对照）三组共23例心脏标本进行H．E和HHF35免疫组化观察．结果：9例SMDS中，8例心传导系统及心肌细胞出现小灶性HHF35阴性缺染区，而H．E染色未发现明显梗死灶；冠心病组7例均出现不同程度的心肌细胞缺染，呈广泛大面积分布；对照组心肌细胞、心传导系统及血管壁里均匀一致的阳性染色．表明部分SMDS死前已有早期心肌缺血或梗死等病变，其死亡原因应为急性心功能不全而致猝死．
In order to investigate the relationship between the cause of death and sudden cardiac death in young adults with sudden death syndrome (SMDS), 23 heart specimens of three groups of SMDS, coronary heart disease and non-cardiovascular death (normal control) were performed. E and HHF35 immunohistochemistry. Results: In 9 cases of SMDS, 8 cases of cardiac conduction system and myocardial cells appear focal HNF35 negatively infected area, while H. There was no obvious infarction in E staining. Seven cases of CHD group showed different degrees of cardiomyocyte infection, which were widely distributed in large area. The control group had uniform positive staining of cardiomyocytes, cardiac conduction system and blood vessel wall. Show that some SMDS died before myocardial infarction and other early myocardial lesions, the cause of death should be sudden cardiac death caused by acute death.