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异烟醯肼(Isonicotinyl hydrazide),商业名称为雷米封(Remifon),是一种新的治疗结核症的药品,它的治疗价值,虽有一些文献发表,但还在临床试验阶段,没有普遍应用。制造方法比对氨基水杨酸、链霉素等容易,国内已有药厂综合制造。本文是摘译英国药剂学与药理学杂志十月号内的二篇文献,主要的目的,一方面是介绍鉴别法与含量测定法,另方面是学习科学家们怎样去确定一种新的药品的鉴别与含量测定法的方法。
Isonicotinyl hydrazide, a trade name for Remifon, is a new drug for the treatment of tuberculosis. Its therapeutic value, although published in some publications, is still in the clinical trial stage and is not universal. application. The manufacturing method is easier than amino salicylic acid, streptomycin, etc., and domestic pharmaceutical companies have integrated manufacturing. This article is an excerpt from the two articles in the October issue of the British Journal of Pharmacy and Pharmacology. The main purpose is to introduce identification and content determination on the one hand, and on the other hand, to learn how scientists determine a new drug. Identification and assay methods.