论文部分内容阅读
目的 探讨小剂量 13 1碘分次疗法治疗毒性弥漫性甲状腺肿的疗效。 方法 13 1I剂量降至常规计算用量的 1/2～ 2 /3 ,1次顿服 ,3个月为 1个疗程 ,进行疗效复查 ,总剂量 1.5～ 8 mCi。 结果 3 2 7例患者中 ,痊愈 3 0 9例 ,治愈率 94.5 % ,未愈 14例 ,占 4.3 % ,4例出现早发甲状腺功能低下 (甲低 ) ,经治疗或观察半年后恢复。治愈总疗程 1～ 3个 ,时间 3～ 9个月。痊愈病例中 ,服药 1个疗程治愈 98人 ( 3 1.7% ) ,2个疗程治愈 182人 ( 5 8.9% ) ,3个疗程治愈 2 9人( 9.4% ) ,观察 5～ 11年 ,3 0 9例治愈患者中未出现甲亢复发或晚发甲低。 结论 小剂量 13 1I是治疗毒性弥漫性甲状腺肿安全、有效的方法。
Objective To investigate the curative effect of small dose 13 1 iodine fractionating therapy on toxic diffuse goiter. Method 13II dose reduced to the conventional calculation of the amount of 1/2 ~ 2/3, 1 times Dayton clothing, 3 months for a course of treatment for review, the total dose of 1.5 ~ 8 mCi. Results Among 327 cases, 399 cases were cured, the cure rate was 94.5%, 14 cases were unhealed, accounting for 4.3%. Four cases had early hypothyroidism (hypothyroidism), and recovered after six months’ treatment or observation. Cure the total course of 1 to 3, time 3 to 9 months. Among the cured cases, 98 were cured in 1 course (3 1.7%), 182 were cured in 2 courses (59.9%), 29 were cured in 3 courses (9.4%), 5 to 11 years were observed Cases of patients without recurrence of hyperthyroidism or late hypothyroidism. Conclusion Low-dose 131I is a safe and effective treatment for toxic diffuse goiter.