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造血干细胞移植 (ＨＳＣＴ)已成为目前治疗白血病及某些实体瘤的有效方法之一 ,但移植相关并发症和移植物抗宿主病 (ＧＶＨＤ)的发生使ＨＳＣＴ应用受到限制。而ＧＶＨＤ的预防措施如Ｔ细胞去除ＴＣＤ)和免疫抑制剂的应用同时也减弱移植物抗白血病 (ＧＶＬ)效应和有效植活。明
Hematopoietic stem cell transplantation (HSCT) has become one of the effective methods for the treatment of leukemia and some solid tumors. However, the development of graft-versus-host disease (GVHD) has limited the use of HSCT. While prevention of GVHD such as T cell depletion of TCD) and immunosuppressive agents also attenuate graft versus leukemia (GVL) effects and effective engraftment. Bright