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目的观察复方甲硝唑栓联合倍美力软膏治疗老年性阴道炎的临床效果,探索治疗老年性阴道炎的有效方案。方法选择2010年4月—2012年9月收治的老年性阴道炎患者122例,随机分为观察组与对照组各61例,观察组采用复方甲硝唑栓联合倍美力软膏治疗,对照组仅给予复方甲硝唑栓治疗,比较治疗效果以及不良反应发生率。计量资料采用u检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果治疗后观察组患者雌二醇[(154.97±49.35)pmol/L]显著高于对照组[(43.28±26.49)pmol/L],尿促卵泡素[(35.73±11.95)U/L]显著低于对照组[(54.39±17.95)U/L],两组比较差异有统计学意义(P<0.05)。观察组总有效率(96.72%)高于对照组(67.21%),两组比较差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论在复方甲硝唑栓基础上联合使用倍美力软膏治疗老年性阴道炎效果满意,可改善患者的性激素水平,值得临床应用推广。
Objective To observe the clinical effect of compound metronidazole suppository combined with pimetic ointment in the treatment of senile vaginitis and to explore an effective treatment for senile vaginitis. Methods 122 cases of senile vaginitis admitted from April 2010 to September 2012 were randomly divided into observation group and control group with 61 cases each. The observation group was treated with compound metronidazole suppository and times mei-li ointment, and the control group Only compound metronidazole suppository treatment, the treatment effect and the incidence of adverse reactions were compared. Measurement data using u test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results After treatment, the estradiol level in the observation group was significantly lower than that in the control group [(43.28 ± 26.49) pmol / L and [35.73 ± 11.95] U / L] Control group [(54.39 ± 17.95) U / L], the difference between the two groups was statistically significant (P <0.05). The total effective rate in the observation group (96.72%) was higher than that in the control group (67.21%). There was significant difference between the two groups (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The combined metronidazole suppository on the basis of the United States beverly ointment in the treatment of senile vaginitis satisfactory results, can improve the level of sex hormones in patients, it is worth promoting the clinical application.