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肿瘤坏死因子α(TNF-α)是一种分子量为17kD的细胞因子,主要由巨噬细胞产生。目前认为TNF-α的体内抗肿瘤效应系由对肿瘤相关性血管系统的选择性破坏所致。 重组DNA技术使合成TNF-α成为可能,人们对其
Tumor necrosis factor alpha (TNF-α) is a 17 kD cytokine that is mainly produced by macrophages. The in vivo antitumor effect of TNF-[alpha] is currently believed to result from the selective destruction of the tumor-associated vasculature. Recombinant DNA technology makes it possible to synthesize TNF-α, people