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目的探讨学龄前儿童低骨密度与血钙、铁、锌、镁、铜5种血清微量元素的关系。方法随机抽取2013年3月-2014年12月该院儿童保健门诊0~6岁健康儿童216例,利用Sun Light 7000型骨密度仪测定骨密度SOS值,同时测定左手无名指末梢非空腹血钙、铁、锌、镁、铜水平。结果正常骨密度组133例,低骨密度组83例,两组儿童年龄、血钙、铁、锌、身高及体重比较,差异具有统计学意义(P<0.05)。正常骨密度组中低血清铁的儿童占32.33%,而低骨密度组中为48.19%,差异有统计学意义(P=0.020)。偏相关分析校正年龄、性别,结果显示血铁和血锌与SOS值之间仍呈正相关(P<0.05),偏相关系数分别为0.211与0.163。结论儿童低骨密度发生率与血铁、锌等微量元素缺乏有关,应注重儿童缺铁、缺锌的防治,降低低骨密度的发生。
Objective To explore the relationship between low BMD of preschool children and five serum trace elements of calcium, iron, zinc, magnesium and copper in preschool children. Methods A total of 216 healthy children aged 0-6 years from March 2013 to December 2014 in our hospital were selected randomly. The bone mineral density (SOS) was measured by Sun Light 7000 bone mineral density meter. Meanwhile, the left- Iron, zinc, magnesium, copper level. Results There were 133 cases in normal BMD group and 83 in low BMD group. There were significant differences in age, serum calcium, iron, zinc, height and weight between the two groups (P <0.05). Children with low serum iron in normal BMD group accounted for 32.33%, while in low BMD group was 48.19%, the difference was statistically significant (P = 0.020). Partial correlation analysis adjusted age and gender, and the results showed that there was still a positive correlation between serum iron and blood zinc and SOS (P <0.05). The partial correlation coefficients were 0.211 and 0.163 respectively. Conclusions The incidence of low BMD in children is related to the lack of trace elements such as iron, zinc and so on. Children with iron deficiency and zinc deficiency should be emphasized to reduce the occurrence of low BMD.