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1976年Lindstrom在一痉挛性腹痛、慢性水泻的中年女性病例中,首次描述了胶原性结肠炎(CC)的临床病理本质。其后,在英文文献中至少报道了48例有显著一致性的临床、内镜及病理特征的本病患者。临床及实验室特征:患者年龄23～86岁(平均54岁)。女性4倍于男性。主要症状为间歇性非血性水泻,可日达20次。常有绞窄性腹痛、恶心、呕吐、胀气、大便失禁含粘液及不同程度体重减轻。腹泻常持续数月至
In 1976, Lindstrom for the first time described the clinical and pathological nature of collagen-colitis (CC) in a middle-aged female with spastic abdominal pain and chronic watery diarrhea. Subsequently, in the English literature at least reported in 48 cases of significant clinical, endoscopic and pathological features of the patients. Clinical and laboratory characteristics: Patients aged 23 to 86 years (mean 54 years). Female 4 times more than men. The main symptom is intermittent non-bloody diarrhea, up to 20 times daily. Often strangulating abdominal pain, nausea, vomiting, flatulence, fecal incontinence with mucus and varying degrees of weight loss. Diarrhea often lasts for months