3例儿童罕见嗜血综合症合并肝功能障碍的实验室各指标结果分析并文献学习

• 作 者: 李秋琼 肖美芳 薛静 陈芬
• 机 构: 海南省妇女儿童医学中心检验科 海南 海口 571100;海南省妇女儿童医学中心检验科 海南 海口 571100;海南省妇女儿童医学中心检验科 海南 海口 571100;海南省妇女儿童医学中心检验科 海
• 出 处: 健康必读
• 发表日期: 2021年26期
• 关键词: children Hemophilic yndrome Results of laboratory indicators early diagnosize

目的:分析收集我院3例儿童罕见嗜血细胞综合征(HPS)合并肝功能障碍的实验室各指标结果及其相关的临床资料.方法:对2019年1月1日至2020年12月31日在我院确诊为HPS的3例患儿合并肝功能障碍的实验室各指标结果及其临床特点等进行分析,并复习相关文献.结果 1例收治后即可明确诊断,1例初误诊为上呼吸道感染,另一例初误诊为皮疹,实验室结果均以血细胞减少,凝血功能障碍(纤维蛋白原明显降低),肝功能障碍,乳酸脱氢酶升高,高脂血症(三酰甘油升高),并血清铁蛋白异常升高和心肌酶谱改变等为主.结论:HPS临床表现“,”Objective:To analyze and collect the laboratory index results and related clinical data of 3 cases of children with rare hemophilic cell syndrome (HPS) complicated with liver dysfunction in our hospital, in order to improve the understanding of this rare disease.Methods:To analyze and collect the laboratory index results and related clinical data of 3 cases of children with rare hemophilic cell syndrome (HPS) complicated with liver dysfunction in our hospital, in order to improve the understanding of this rare disease, so as to provide better services for early clinical diagnosis and treatment.Results: 1 case of diagnosis after treated, 1 case was misdiagnosed as upper respiratory tract infection, at the beginning of another example of the early misdiagnosed as rash, laboratory results in blood cells decreases, blood coagulation dysfunction (fibrinogen significantly decreased), liver function obstacle, elevated lactate dehydrogenase,Hyperlipidemia (elevated triglyceride), abnormal increase in serum ferritin and changes in myocardial enzyme profile were the main factors. Conclusion:The clinical manifestations of HPS are varied and the disease progresses rapidly, relevant laboratory examinations should be conducted timely and accurately to avoid misdiagnosis and mistreatment.