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目的研究肝素治疗小儿紫癜性肾炎的临床疗效。方法将收治的82例小儿紫癜性肾炎患者随机分为两组,常规组41例,均按小儿紫癜性肾炎常规治疗;治疗组41例,均在常规治疗的基础上加用肝素治疗。疗程均为2周,治疗后随访3个月,治疗前后进行综合分析。结果常规组总有效率为82.92%(34/41),治疗组总有效率为92.68%(38/41),两组疗效比较差异有统计学意义(P<0.05)。结论肝素是治疗和预防小儿紫癜性肾炎的主要措施,值得临床推广。
Objective To study the clinical effect of heparin on purpura nephritis in children. Methods 82 cases of children with purpura nephritis were randomly divided into two groups, routine group of 41 cases, according to the routine treatment of children with purpura nephritis; the treatment group of 41 cases, both in the conventional treatment plus heparin therapy. The course of treatment was 2 weeks, followed up for 3 months after treatment, before and after treatment for a comprehensive analysis. Results The total effective rate was 82.92% (34/41) in the conventional group and 92.68% (38/41) in the treatment group. The difference between the two groups was statistically significant (P <0.05). Conclusion Heparin is the main treatment and prevention of purpura nephritis in children, which is worthy of clinical promotion.