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目的:探讨前列腺黏液腺癌的病理和诊疗特点。方法:回顾性分析我院1995年1月~2011年3月收治的2例前列腺黏液腺癌患者的临床资料,并结合文献复习,分析其特点。结果:2例患者年龄分别为73和84岁,因不同程度的排尿困难入院。1例误诊为前列腺增生,行经尿道前列腺电切术;另1例直肠指检、B超、CT、MRI及PSA检查均提示为前列腺癌,行穿刺活检后确诊,根据患者全身状况行硬膜外麻醉下经尿道前列腺电切术,以改善排尿症状,术后病理检查回报为前列腺黏液腺癌,免疫组织化学检查有较特异性表现。术后给予抗雄激素治疗等。结论:前列腺黏液腺癌在前列腺癌中罕见,没有特征性的临床表现,确诊主要依靠病理和免疫组织化学检查;治疗方法可采用根治性前列腺切除术。
Objective: To investigate the pathology and diagnosis and treatment of mucinous adenocarcinoma of the prostate. Methods: The clinical data of 2 patients with mucinous adenocarcinoma of the prostate treated in our hospital from January 1995 to March 2011 were retrospectively analyzed. The characteristics of the patients were reviewed according to the literature review. Results: The two patients were 73 and 84 years old, respectively, due to varying degrees of dysuria admitted to hospital. 1 case misdiagnosed as benign prostatic hyperplasia, transurethral resection of the prostate; the other 1 case of digital rectal examination, B ultrasound, CT, MRI and PSA were prompted for prostate cancer, biopsy confirmed after diagnosis, according to the general condition of patients with epidural Under anesthesia transurethral resection of the prostate to improve the symptoms of urination, postoperative pathological examination of the return of mucinous adenocarcinoma of the prostate, immunohistochemistry have more specific performance. After giving anti-androgen therapy. Conclusions: Prostate mucinous adenocarcinoma is rare in prostate cancer and has no characteristic clinical manifestations. The diagnosis mainly depends on pathology and immunohistochemical examination. Radical prostatectomy may be used in the treatment.