论文部分内容阅读
[目的]评价健脾清热活血方辨治溃疡性结肠炎的疗效。[方法]采用非劣效试验设计,应用随机对照设计,将120例符合诊断标准、纳入标准的溃疡性结肠炎患者随机分为2组,治疗组60例,对照组60例。治疗组予中药复方健脾清热活血方干预12周,对照组予美沙拉嗪干预12周。详细记录治疗前、后患者肠镜及症状变化。[结果]治疗前、后肠镜病变疗效判定,治疗组总有效率为66.66%,对照组总有效率为63.33%,在促进溃疡愈合方面,2组疗效无差异(P>0.05);治疗前、后症状积分判定疗效,治疗组总有效率为78.33%,对照组总有效率为61.66%,在改善临床症状方面,治疗组疗效优于对照组(P<0.05)。[结论]健脾清热活血方具有提高溃疡性结肠炎愈合质量、缓解其临床症状的功效,值得临床推广应用。
[Objective] To evaluate the curative effect of Jianpi Qingre Huoxue Decoction on ulcerative colitis. [Methods] With non-inferiority trial design, 120 patients with ulcerative colitis who met the diagnostic criteria and were included in the standard were randomly divided into two groups: 60 cases in the treatment group and 60 cases in the control group. In the treatment group, the intervention of Jianpi Qingre Huoxue Recipe was given for 12 weeks, while the control group was given Mesalazine for 12 weeks. Detailed records of patients before and after treatment of colonoscopy and symptoms. [Results] The results showed that the total effective rate was 66.66% in the treatment group and 63.33% in the control group. There was no significant difference between the two groups (P> 0.05) before treatment After symptom score, the total effective rate was 78.33% in the treatment group and 61.66% in the control group. The curative effect of the treatment group was better than that of the control group (P <0.05) in improving the clinical symptoms. [Conclusion] Jianpi Qingre Huoxue Decoction can improve the healing quality of ulcerative colitis and relieve the clinical symptoms, which deserves clinical application.