MiR-135a biogenesis and regulation in malignancy:a new hope for cancer research and therapy

• 作 者: Zhe Cao Jiangdong Qiu Gang Yan
• 机 构: DepartmentofGeneralSurgery,DepartmentofNuclearMedicine,ClinicalImmunologyCenter
• 出 处: 癌症生物学与医学:英文版
• 发表日期: 2020年3期
• 关键词: Biomarker cancer CHEMORESISTANCE epithelial-mesenchymal transition miR-135a THER
• 基金项目: This work was supported by grants from the National Natural Science Foundation of China(Grant Nos.81772639,81802475,81972258,and 81974376),the Natural Science Foundation of Beijing(Grant No.7192157),C

MicroRNAs(miRNAs)are evolutionarily conserved small non-coding RNAs that affect posttranscriptional regulation by binding to the 3′-untranslated region of target messenger RNAs.MiR-135a is a critical miRNA that regulates gene expression,and many studies h