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血吸虫感染存在着伴随免疫的现象,其主要特点是宿主产生的免疫力仅针对再次入侵的幼小童虫,体内已存在的成虫通过获得宿主抗原,可以逃避宿主免疫系统的识别和杀伤。童虫必需摄入宿主的红细胞方能在宿主体内继续生长、发育。早在70年代初即有学者报道在血吸虫的表膜上存在着特异性的宿主血型所决定的抗原决定簇。以后有学者进一步证实体外培养中的童虫表膜具有A,B血型抗原。作者用穿皮法制备曼氏血吸虫童虫。收集童虫后分置4个雷氏管中,加入等量
Schistosoma infection is accompanied by the phenomenon of immunity. Its main feature is that the immunity generated by the host is only directed against the young juvenile re-invasion. Existing adult worms can evade the identification and killing of the host’s immune system by obtaining the host antigens. Schistosomiasis must be ingested into the host’s red blood cells in the host body to continue to grow and develop. As early as the early 1970s, some scholars reported that there are specific epitopes determined by the blood type of the host on the surface membrane of Schistosoma japonicum. Later, some scholars further confirmed that in vitro culture Schistosoma capsid with A, B blood group antigen. The author uses the skin preparation method to produce Schistosoma mansoni. Juveniles were collected after the separation of 4 Ryder tube, adding the same amount