Hepatitis C virus NS5A region mutation in chronic hepatitis C genotype 1 patients who are non-respon

• 作 者: Paloma Mu?oz de Rueda José
• 机 构: ResearchSupportUnit,InstitutodeInvestigació,nBiosanitaria,CIBERehd,UnitforClinicalManagementofDi
• 出 处: 世界胃肠病学杂志：英文版
• 发表日期: 2017年25期
• 关键词: 基于干扰素的治疗 没有干扰素的治疗 长期的丙肝 NS5A 区域 持续 virological 反应 变化数 Interferon-based therapy
• 基金项目: Supported by“Consejería de Salud de la Junta de Andalucía”,No.PI0137/07,“Instituto de Salud CarlosⅢ”,No.FISIntrasalud PI010/717

AIM To determine the number of mutations in the NS5 A region of the hepatitis C virus(HCV) and its relationship to the response to antiviral therapy in patients with chronic hepatitis C genotype 1 who are non-responders to two or more treatments. METHODS