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促黄体激素释放激素(LHRH)是控制哺乳动物繁殖的脑多肽。用化学方法将LHRH与载体蛋白相连构成化学结合疫苗免疫动物,已证明是安全有效的预防繁殖的手段。但化学结合不能获得结构均一的抗原。本文旨在构建一种质粒,使其表达结构均一的并具有LHRH免疫原性的嵌合
Luteinizing hormone releasing hormone (LHRH) is a brain polypeptide that controls mammalian reproduction. Chemically linking LHRH to a carrier protein to form a chemically-bound vaccine for immunization of animals has proven to be a safe and effective means of preventing reproduction. However, chemical binding can not obtain a homogeneous antigen. The purpose of this paper is to construct a plasmid that allows its expression to be homogenous and has a chimeric LHRH immunogenicity