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丙氟哌酸是一种新的羧基喹啉化合物,在体外也有抗脑膜炎奈瑟氏菌的作用。口服丙氟哌酸500mg,2次/日,每疗程5天,可成功地根除鼻咽部脑膜炎奈瑟氏菌。为此,作者作了开放性研究,测试口服单剂丙氟哌酸根除健康人鼻咽部脑膜炎奈瑟氏菌带菌者的疗效。 211例健康年青人中发现25例(11.9%)为持久性鼻咽部脑膜炎奈瑟氏菌带菌者,对12例进行选择性的研究。每例持久带菌者提供了医疗史并做了体检,还做了预处理实验室测试(全血计数,尿分析和血尿氮、肌酐、天门冬氨酸盐转氨酶,丙氨酸转氨酶,全胆红素和硷性磷酸酯酶值的测定)和第三次鼻
Ciprofloxacin is a new carboxyquinoline compound that is also resistant to Neisseria meningitidis in vitro. Oral norfloxacin 500mg, 2 times / day, every 5 days of treatment, can be successfully eradicated nasopharyngeal meningitidis meningitidis. To this end, the authors made an open-label study to test the efficacy of oral single-dose propofolmic acid in the eradication of Neisseria meningitidis in healthy subjects. Twenty-five of the 211 healthy young adults (11.9%) were persistent Neisseria meningitidis with nasopharynx, and 12 were studied selectively. Each case of a long-lasting carrier provided a medical history and did a physical examination, and pretreatment laboratory tests (whole blood count, urinalysis, hematuria, creatinine, aspartate aminotransferase, alanine aminotransferase, Determination of Superoxide and Alkaline Phosphatase) and Third Nose