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目的探讨部分脾动脉栓塞治疗脾功能亢进的疗效及其可能存在的并发症。方法36例脾功能亢进患者(男28例,女8例),所有病人均有不同程度贫血,部分患者上消化道出血和食管胃底静脉曲张,所有患者术前检查排除手术禁忌证后行脾动脉栓塞术,栓塞栓塞范围控制在50%～70%左右,术后随访1到3年,观察患者白细胞及血小板变化及出现的不良反应。结果经1～3年的随访观察,血小板或白细胞计数在栓塞后一年仍保持明显升高并维持3年以上,几乎所有病人术后均有不同程度发热,2例病人术后左侧胸腔少量积液,所有病人未发生脾脓肿,肝功能衰竭及其他并发症。结论部分脾动脉栓塞治疗可有效地疗脾功能亢进,且无明显严重并发症。
Objective To investigate the curative effect and possible complications of partial splenic arterial embolization in the treatment of hypersplenism. Methods Thirty-six patients with hypersplenism (28 males and 8 females) were enrolled in this study. All patients had different degrees of anemia, upper gastrointestinal bleeding and esophagogastric varices in all patients. All patients underwent preoperative examination to exclude splenectomy Arterial embolization, embolization embolization range control in about 50% to 70%, after 1 to 3 years follow-up, observation of patients with leukocyte and platelet changes and adverse reactions. Results After 1 to 3 years of follow-up, the platelet or white blood cell count remained significantly elevated for more than 3 years one year after embolization. Almost all patients had varying degrees of fever postoperatively. A small amount of left thoracic cavity was found in 2 patients Fluid, all patients did not occur spleen abscess, liver failure and other complications. Conclusion Some splenic arterial embolization can effectively treat hypersplenism without obvious serious complications.