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得克萨斯州Adderson医院最近报导了1,000例成人急性白血病患者在接受诱导缓解化疗的同时有329例(32.9%)发生了口腔感染,其中霉菌感染占50%,单纯疱疹占15%,革兰氏阴性杆菌占25%,革兰氏阳性球菌占10%。尸检的材料证明75%急性白血病、50%淋巴瘤、50%的转移瘤患者死于感染。进行化疗的癌症病人发生感染是与肿瘤病变的病理生理过程、化疗方案的类型、药物及疾病对患者全身和局部的免疫影响等因素有关。为了观察以上因素是否也适于口腔感染,该院对接受化疗的1000例实体瘤病人进行了口腔感染的频率和感染类型的观察。其
Recently, Adderson Hospital in Texas reported oral infections in 329 patients (32.9%) of 1,000 adults with acute leukemia while receiving induction of remission chemotherapy. Among them, 50% were mold infections, 15% were herpes simplex and Gram-negative bacilli Accounting for 25%, Gram-positive cocci accounted for 10%. Autopsy evidence of 75% of acute leukemia, 50% of lymphoma, 50% of patients with metastatic disease died of infection. Infections of cancer patients undergoing chemotherapy are related to the pathophysiological process of tumor lesions, the type of chemotherapy regimen, and the effects of drugs and diseases on systemic and local immune effects of the patient. In order to see whether the above factors are also suitable for oral infections, the hospital observed the frequency of oral infections and the type of infection in 1000 solid tumor patients undergoing chemotherapy. its