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采用单向琼脂扩散法检测20例慢性苯中毒患者及20例健康人血液Cu.Zn-SOD含量,发现患者组显著高于对照组,P<.01。提示苯中毒对作业工人Cu.Zn-SOD含量有明显影响。对其中10例患者试用输注人胎肝细胞悬液(FLC)进行治疗前后观察,其结果表明:FLC输注能在近期内使Cu.Zn-SOD含量恢复正常,并使WBC回升,外周血淋转率相应增高,认为这些改变与胎肝悬液中的多种活性物质的作用有关。
One-way agar diffusion method was used to detect the blood levels of Cu.Zn-SOD in 20 patients with chronic benzene poisoning and 20 healthy persons. The patients in the group were significantly higher than those in the control group (P <.01). It is suggested that benzene poisoning has a significant effect on Cu.Zn-SOD content of workers. The results of 10 patients before and after the treatment of infusion of fetal liver cell suspension (FLC) showed that FLC infusion could restore the content of Cu.Zn-SOD to normal in the near future and lead to the recovery of WBC, Corresponding increase in the rate of lean conversion, that these changes and fetal liver suspension in the role of a variety of active substances.