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目的:观察厄贝沙坦联合葛根素治疗糖尿病肾病的临床疗效。方法:65例糖尿病肾病患者随机分为治疗组34例和对照组31例,在常规治疗糖尿病基础上,对照组加用厄贝沙坦,治疗组加用厄贝沙坦联合葛根素,观察2组患者治疗前后尿白蛋白排泄率、血肌酐、尿素氮的变化。结果:2组尿白蛋白排泄率、血肌酐、尿素氮下降,治疗组优于对照组,差异有统计学意义(P<0.05)。结论:厄贝沙坦联合葛根素能改善肾功能,延缓病情进展。
Objective: To observe the clinical efficacy of irbesartan and puerarin in the treatment of diabetic nephropathy. Methods: Sixty-five patients with diabetic nephropathy were randomly divided into treatment group (n = 34) and control group (n = 31). On the basis of routine treatment of diabetes, irbesartan was given to the control group. Irbesartan and puerarin were used in the treatment group. Urine albumin excretion rate, serum creatinine and urea nitrogen in group before and after treatment. Results: The urinary albumin excretion rate, serum creatinine and urea nitrogen decreased in the two groups, and the difference was statistically significant (P <0.05). Conclusion: Irbesartan and puerarin can improve renal function and delay the progression of the disease.