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目的探讨常规治疗小儿急性腹泻时佐以葡萄糖酸锌的临床效果。方法将东兰县人民医院2010年2月～2012年2月收治的小儿急性腹泻患者89例随机分为观察组45例和对照组44例,对照组施以常规治疗方法,包括补充水电解质、纠正酸碱平衡紊乱、蒙脱石散口服等,观察组在其基础之上加用葡萄糖酸锌口服液,比较两组患儿的临床症状恢复情况。结果观察组总有效率97.8%明显高于对照组88.6%,两组比较有显著性差异(P<0.05);观察组患儿的止泻、止吐、退热、脱水纠正、住院时间均短于对照组,两组比较差异有统计学意义(P<0.05)。结论治疗小儿急性腹泻在常规治疗基础上加用葡萄糖酸锌口服液可有效改善临床症状,减轻病情,缩短腹泻病程,疗效满意,值得推广应用。
Objective To investigate the clinical effects of zinc gluconate in routine treatment of acute diarrhea in children. Methods Eighty-nine children with acute diarrhea admitted to Donglan People’s Hospital from February 2010 to February 2012 were randomly divided into observation group (n = 45) and control group (n = 44). The control group was given routine treatment including water and electrolyte supplement, Correction of acid-base balance disorders, such as oral montmorillonite, the observation group on the basis of plus oral gluconate solution, the clinical symptoms of two groups were compared. Results The total effective rate in observation group was 97.8%, which was significantly higher than that in control group (88.6%), there was significant difference between two groups (P <0.05). Diarrhea, antiemetic, antipyretic, dehydration correction and hospital stay in observation group were all short In the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion The treatment of acute diarrhea in children with conventional treatment based on the addition of oral gluconate solution can effectively improve the clinical symptoms, reduce the disease and shorten the course of diarrhea, the curative effect is satisfactory, which is worth popularizing and applying.