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目的:探讨贲门癌术后吻合口瘘的临床治疗方法和效果。方法:从我院2013年1月-2015年12月收治的贲门癌术后吻合口瘘患者中随机选取64例进行研究,并根据其入院顺序分为两组,每组32例。对照组单纯采用全肠外营养支持,观察组则在此基础上采用生长抑制素和肠内营养支持,对两组患者的临床治疗效果进行对比。结果:(1)对照组病死率为43.75%,明显高于观察组的18.75%,组间差异显著(P<0.05)。(2)观察组的瘘口愈合时间明显短于对照组,且胸腔闭式引流量和胃肠减压量均少于对照组,各指标差异均有意义(P<0.05)。结论:采用生长抑制素以及肠内外营养支持治疗贲门癌术后吻合口瘘具有显著疗效,可减少病死率,缩短愈合时间,有助于促进预后,适合进行临床推广。
Objective: To explore the clinical treatment of gastric cardia cancer anastomotic fistula and its effect. Methods: Sixty-four patients randomly selected from our hospital from January 2013 to December 2015 for cardia cancer with anastomotic fistula were divided into two groups (n = 32 in each group). The control group was treated with total parenteral nutrition alone, and the observation group was treated with the combination of somatostatin and enteral nutrition. The clinical effects of the two groups were compared. Results: (1) The case fatality rate in the control group was 43.75%, which was significantly higher than that in the observation group (18.75%). There was significant difference between the two groups (P <0.05). (2) The fistula healing time in the observation group was significantly shorter than that in the control group, and the volume of closed thoracic drainage and decompression of the gastrointestinal tract were less than those in the control group (P <0.05). Conclusion: The use of somatostatin and enteral nutrition support for the treatment of cardia cancer after anastomotic fistula has a significant effect, can reduce the mortality, shorten the healing time, help to promote the prognosis, suitable for clinical promotion.