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对200名使用不同避孕方法的妇女按随机表分为四组,包括①惰性IUD(Lippes C)为对照组、②Cu-IUD、③OC三相口服药片和④复方避孕针作比较,对他们的血脂作前瞻性研究。选择年龄为20～34岁,有生育力,6个月内未用过避孕药,不吸烟,非肥胖症(体重不超过标准体重20％),无高血压,肝功能及葡萄糖耐量试验正常的妇女为研究对象。完成一年研究的168名妇女中,对照组47例,Cu-IUD组(Nova T)48例,OC组服△~(15)-D-甲炔诺(?)+炔雌醇的三相片33例,避孕针组40例(每月使用庚炔酮50mg十戊酸雌二醇5mg)。所有对象于研究开始及用后第1、6、12个月时分别于周期第1～7天内(大多数为第1天)取空腹血,测定总血脂、总胆固醇、HDL胆固醇、LDL胆固醇及甘油三酯。用多重比较对1、 6、12个月时组间及各组研究前后的血脂值进行统计分析。结果表明血清总脂对照组和Cu-IUD组,OC组间无显著差异,而避孕针组在用药1、6个月时显著低于对照组及本身用药前水平,但12个月时与对
200 women using different methods of contraception were randomly divided into four groups according to their randomness table, including: ① Ipseus IUD (Lippes C) as control group, ② Cu-IUD, ③OC three-phase oral tablets and ④ compound contraceptives for comparison, For the prospective study. Choose from 20 to 34 years of age, fertility, no contraceptives within 6 months, non-smoking, non-obesity (body weight does not exceed 20% of standard body weight), no hypertension, liver function and normal glucose tolerance test Women as research subjects. Of the 168 women who completed the one-year study, 47 were in the control group, 48 in the Cu-IUD group (Nova T), and three (3) -phase in the OC group with Δ15 (15) -D- 33 cases, contraceptive group 40 cases (monthly use of heptenoside 50mg estradiol pentanoate 5mg). All subjects were given fasting blood at the beginning of the study and at the first, the sixth and the 12th months respectively after the first 1-7 days of the cycle (most of the first day). Total cholesterol, total cholesterol, HDL cholesterol, LDL cholesterol and Triglycerides. Multiple comparisons were used to statistically analyze the blood lipid values of the groups before and after the study at 1, 6 and 12 months. The results showed that serum total fat control group and Cu-IUD group, OC group no significant difference, while the contraception group 1,6 months of medication was significantly lower than the control group and their pre-medication levels, but at 12 months with