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外源性前列腺素E_1(PGE_1)具有抗动脉硬化,扩张血管,抑制血小板聚集,扩张支气管平滑肌,改善肺通气,扩张肺血管,降低肺血管阻力,正性肌力作用及调节免疫机能作用,广泛应用于临床,治疗多种疾病,如脑梗死,冠心病,支气管哮喘,肺动脉高压,心功能不全,消化性溃疡,糖尿病的神经病变,肢体动脉闭塞性疾病,手术后心衰,呼吸窘迫综合征等。但该药在治疗中不良反应的出现常使一些患者不能忍受而中断治疗。1998年2月至12月间我们共统计3200例中出现的10例不良反应,现报告如下。临床资料
Exogenous prostaglandin E_1 (PGE_1) has anti-atherosclerosis, dilates blood vessels, inhibits platelet aggregation, expands bronchial smooth muscle, improves pulmonary ventilation, expands pulmonary blood vessels, reduces pulmonary vascular resistance, positive inotropic effects and modulates immune function. It is used clinically to treat various diseases such as cerebral infarction, coronary heart disease, bronchial asthma, pulmonary hypertension, cardiac insufficiency, peptic ulcer, neuropathy of diabetes, limb arterial occlusive disease, postoperative heart failure, respiratory distress syndrome Wait. However, the emergence of adverse reactions in the treatment of the drug often make some patients can not stand and interrupt treatment. From February to December 1998, we counted 10 cases of adverse reactions in 3200 cases, the report is as follows. clinical information